:root {
  color-scheme: light;
  --navy: #071334;
  --navy-soft: #0c1d49;
  --ink: #0b245d;
  --body: #42506a;
  --muted: #6b7892;
  --pale: #f4f7fb;
  --white: #ffffff;
  --line: #dbe3ef;
  --line-dark: rgba(127, 174, 226, 0.22);
  --blue: #245bff;
  --cyan: #18c7e8;
  --violet: #7b48f3;
  --display: Arial, Helvetica, sans-serif;
  --text: Arial, Helvetica, sans-serif;
}

* { box-sizing: border-box; }
html { scroll-behavior: smooth; background: var(--white); }
body {
  margin: 0;
  min-width: 320px;
  background: var(--white);
  color: var(--body);
  font-family: var(--text);
  font-size: 1rem;
  line-height: 1.65;
  -webkit-font-smoothing: antialiased;
}
body.menu-open { overflow: hidden; }
a { color: inherit; }
img { display: block; max-width: 100%; }
h1, h2, h3, p, figure { margin-top: 0; }
h1, h2, h3 { color: var(--ink); font-family: var(--display); }

html.preview-locked,
html.preview-locked body {
  min-height: 100%;
  overflow: hidden;
  background: #030817;
}
html.preview-locked body > :not(.preview-gate) { display: none !important; }
.preview-gate[hidden] { display: none; }
.preview-gate {
  position: fixed;
  z-index: 1000;
  inset: 0;
  min-width: 320px;
  min-height: 100vh;
  padding: clamp(1.25rem, 4vw, 3rem);
  display: grid;
  place-items: center;
  overflow-y: auto;
  background:
    radial-gradient(circle at 80% 18%, rgba(123, 72, 243, 0.19), transparent 30rem),
    radial-gradient(circle at 12% 82%, rgba(24, 199, 232, 0.13), transparent 28rem),
    linear-gradient(rgba(3, 8, 23, 0.87), rgba(3, 8, 23, 0.95)),
    url("./matrix-hero.webp") center / cover no-repeat;
  color: white;
}
.preview-gate__panel {
  width: min(31rem, 100%);
  padding: clamp(1.75rem, 6vw, 3rem);
  border: 1px solid rgba(127, 174, 226, 0.28);
  border-radius: 0.75rem;
  background: rgba(7, 19, 52, 0.94);
  box-shadow: 0 2rem 5rem rgba(0, 0, 0, 0.38);
  backdrop-filter: blur(18px);
}
.preview-gate__logo {
  width: min(17rem, 82%);
  margin-bottom: 2.3rem;
  padding: 0.65rem 0.85rem;
  border-radius: 0.3rem;
  background: white;
}
.preview-gate__eyebrow {
  margin-bottom: 0.65rem;
  color: #77def1;
  font-size: 0.76rem;
  font-weight: 800;
  letter-spacing: 0.16em;
  text-transform: uppercase;
}
.preview-gate h1 {
  max-width: 12ch;
  margin-bottom: 0.9rem;
  color: white;
  font-size: clamp(2rem, 7vw, 3.1rem);
  line-height: 1.02;
  letter-spacing: -0.045em;
}
.preview-gate__intro {
  max-width: 35rem;
  margin-bottom: 2rem;
  color: #c2cce0;
  line-height: 1.55;
}
.preview-gate__form label {
  display: block;
  margin-bottom: 0.5rem;
  color: #dce5f5;
  font-size: 0.84rem;
  font-weight: 700;
}
.preview-gate__field {
  display: grid;
  grid-template-columns: 1fr auto;
  overflow: hidden;
  border: 1px solid rgba(183, 206, 238, 0.42);
  border-radius: 0.35rem;
  background: rgba(255, 255, 255, 0.08);
}
.preview-gate__field:focus-within {
  border-color: var(--cyan);
  box-shadow: 0 0 0 3px rgba(24, 199, 232, 0.14);
}
.preview-gate__field input {
  width: 100%;
  min-width: 0;
  padding: 0.88rem 1rem;
  border: 0;
  outline: 0;
  background: transparent;
  color: white;
  font: inherit;
}
.preview-gate__reveal {
  padding: 0 1rem;
  border: 0;
  background: transparent;
  color: #9de8f5;
  font: inherit;
  font-size: 0.8rem;
  font-weight: 800;
  cursor: pointer;
}
.preview-gate__submit {
  width: 100%;
  margin-top: 0.9rem;
  padding: 0.9rem 1.2rem;
  border: 0;
  border-radius: 0.35rem;
  background: linear-gradient(100deg, var(--cyan), #5b75ff 58%, var(--violet));
  color: white;
  font: inherit;
  font-weight: 800;
  cursor: pointer;
  transition: filter 160ms ease, transform 160ms ease;
}
.preview-gate__submit:hover { filter: brightness(1.08); transform: translateY(-1px); }
.preview-gate__error,
.preview-gate__noscript {
  min-height: 1.5rem;
  margin: 0.75rem 0 0;
  color: #ffb4c2;
  font-size: 0.86rem;
}

.sr-only {
  position: absolute;
  width: 1px;
  height: 1px;
  padding: 0;
  margin: -1px;
  overflow: hidden;
  clip: rect(0, 0, 0, 0);
  white-space: nowrap;
  border: 0;
}
.skip-link {
  position: fixed;
  z-index: 100;
  top: 0.75rem;
  left: 0.75rem;
  transform: translateY(-160%);
  padding: 0.7rem 1rem;
  border-radius: 0.25rem;
  background: var(--navy);
  color: white;
  font-weight: 700;
  text-decoration: none;
}
.skip-link:focus { transform: translateY(0); }
:focus-visible { outline: 3px solid var(--violet); outline-offset: 4px; }

.site-header {
  position: absolute;
  z-index: 30;
  top: 0;
  left: 0;
  right: 0;
  min-height: 6.6rem;
  padding: 1rem clamp(1.25rem, 4vw, 4rem);
  border-bottom: 1px solid var(--line);
  background: rgba(255, 255, 255, 0.96);
  display: grid;
  grid-template-columns: minmax(14rem, 1fr) auto minmax(11rem, 1fr);
  gap: 2rem;
  align-items: center;
}
.brand { display: block; width: min(17rem, 100%); text-decoration: none; }
.brand img { width: 100%; height: auto; }
.site-nav { display: flex; align-items: center; justify-content: center; gap: clamp(1.3rem, 2.5vw, 2.7rem); }
.site-nav a {
  position: relative;
  color: #263b65;
  font-size: 0.92rem;
  font-weight: 700;
  text-decoration: none;
  white-space: nowrap;
}
.site-nav a::after {
  content: "";
  position: absolute;
  left: 0;
  right: 100%;
  bottom: -0.45rem;
  height: 2px;
  background: linear-gradient(90deg, var(--cyan), var(--violet));
  transition: right 180ms ease;
}
.site-nav a:hover::after, .site-nav a:focus-visible::after { right: 0; }
.header-status {
  margin: 0;
  justify-self: end;
  display: flex;
  align-items: center;
  gap: 0.6rem;
  color: var(--muted);
  font-size: 0.78rem;
  font-weight: 700;
  letter-spacing: 0.08em;
  text-transform: uppercase;
}
.header-status span {
  width: 0.55rem;
  height: 0.55rem;
  border-radius: 50%;
  background: var(--violet);
  box-shadow: 0 0 0 0.25rem rgba(123, 72, 243, 0.12);
}
.menu-button { display: none; }

.hero {
  position: relative;
  isolation: isolate;
  min-height: 58rem;
  padding-top: 6.6rem;
  display: grid;
  grid-template-rows: 1fr auto;
  overflow: hidden;
  background: #030817 url("./matrix-hero.webp") center 43% / cover no-repeat;
  color: white;
}
.hero::before {
  content: "";
  position: absolute;
  z-index: -2;
  inset: 0;
  background:
    linear-gradient(90deg, rgba(4, 11, 33, 0.96) 0%, rgba(5, 15, 43, 0.81) 46%, rgba(5, 14, 39, 0.28) 78%, rgba(3, 9, 28, 0.38) 100%),
    linear-gradient(0deg, rgba(3, 10, 31, 0.72), transparent 43%);
}
.hero::after {
  content: "";
  position: absolute;
  z-index: -1;
  inset: 0;
  background: radial-gradient(circle at 72% 42%, rgba(24, 199, 232, 0.08), transparent 25rem);
}
.hero-copy {
  z-index: 2;
  width: min(77rem, 100%);
  padding: clamp(6rem, 10vw, 10rem) clamp(1.5rem, 7vw, 8rem) clamp(4rem, 7vw, 6.5rem);
  align-self: center;
}
.section-label {
  margin-bottom: 1.45rem;
  color: var(--blue);
  font-size: 0.78rem;
  font-weight: 700;
  letter-spacing: 0.16em;
  text-transform: uppercase;
}
h1 {
  max-width: 76rem;
  margin-bottom: 1.75rem;
  color: white;
  font-size: clamp(3.25rem, 6.1vw, 7rem);
  font-weight: 700;
  letter-spacing: -0.055em;
  line-height: 0.96;
}
h1 em {
  color: transparent;
  background: linear-gradient(100deg, #78e7f3, #68b9ff 48%, #b992ff);
  background-clip: text;
  -webkit-background-clip: text;
  font-style: normal;
}
.hero-intro {
  max-width: 49rem;
  margin-bottom: 2.2rem;
  color: #d3def0;
  font-size: clamp(1.05rem, 1.4vw, 1.22rem);
  line-height: 1.72;
}
.hero-actions { display: flex; align-items: center; gap: 1.7rem; flex-wrap: wrap; }
.button {
  display: inline-flex;
  align-items: center;
  justify-content: center;
  min-height: 3.35rem;
  padding: 0.8rem 1.2rem;
  border-radius: 0.25rem;
  font-size: 0.91rem;
  font-weight: 700;
  text-decoration: none;
  transition: transform 160ms ease, box-shadow 160ms ease;
}
.button-primary {
  background: linear-gradient(100deg, var(--blue), #396fe9);
  color: white;
  box-shadow: 0 0.8rem 2rem rgba(36, 91, 255, 0.18);
}
.button-primary:hover { transform: translateY(-2px); box-shadow: 0 1rem 2.3rem rgba(36, 91, 255, 0.25); }
.text-link { color: white; font-size: 0.91rem; font-weight: 700; text-decoration: none; }
.text-link span { margin-left: 0.45rem; color: var(--violet); }
.text-link:hover { color: var(--blue); }

.hero-facts {
  z-index: 2;
  display: grid;
  grid-template-columns: repeat(3, 1fr);
  border-top: 1px solid rgba(171, 206, 240, 0.24);
  background: rgba(3, 10, 30, 0.62);
  backdrop-filter: blur(12px);
}
.hero-facts p {
  margin: 0;
  min-height: 7rem;
  padding: 1.5rem clamp(1rem, 2.2vw, 2.5rem);
  border-right: 1px solid rgba(171, 206, 240, 0.2);
  display: flex;
  flex-direction: column;
  justify-content: center;
}
.hero-facts p:first-child { padding-left: clamp(1.5rem, 7vw, 8rem); }
.hero-facts p:last-child { border-right: 0; }
.hero-facts span { color: #8fdff1; font-size: 0.72rem; font-weight: 700; letter-spacing: 0.1em; text-transform: uppercase; }
.hero-facts strong { margin-top: 0.2rem; color: white; font-size: 0.98rem; }

.section { padding: clamp(5.5rem, 9vw, 9rem) clamp(1.5rem, 7vw, 8rem); }
.section-marker {
  color: #e7edf6;
  font-size: clamp(4rem, 7vw, 8rem);
  font-weight: 700;
  letter-spacing: -0.07em;
  line-height: 0.8;
}
h2 {
  margin-bottom: 0;
  font-size: clamp(2.55rem, 4.9vw, 5.5rem);
  font-weight: 700;
  letter-spacing: -0.052em;
  line-height: 0.98;
}
.lead { color: #1c315e; font-size: clamp(1.2rem, 1.8vw, 1.5rem); line-height: 1.5; }
.materials-intro {
  display: grid;
  grid-template-columns: 0.26fr minmax(20rem, 0.82fr) minmax(20rem, 0.72fr);
  gap: clamp(2rem, 5vw, 6rem);
  align-items: start;
}
.materials-explainer { padding-top: 2.4rem; }
.materials-explainer p:last-child { margin-bottom: 0; color: var(--muted); }

.format-section {
  position: relative;
  isolation: isolate;
  overflow: hidden;
  background: var(--navy);
  color: #c6d1e8;
}
.format-section::before {
  content: "";
  position: absolute;
  z-index: -2;
  inset: 0;
  background-image: url("./matrix-scroll.webp");
  background-repeat: repeat-x;
  background-position: top center;
  background-size: 42rem auto;
  opacity: 0.32;
}
.format-section::after {
  content: "";
  position: absolute;
  z-index: -1;
  inset: 0;
  background: linear-gradient(90deg, rgba(5, 14, 43, 0.99) 0%, rgba(5, 14, 43, 0.78) 52%, rgba(5, 14, 43, 0.92) 100%);
}
.format-inner {
  min-height: 48rem;
  padding: clamp(5.5rem, 9vw, 9rem) clamp(1.5rem, 7vw, 8rem);
  display: grid;
  grid-template-columns: minmax(20rem, 0.78fr) minmax(30rem, 1fr);
  gap: clamp(3rem, 8vw, 9rem);
  align-items: center;
}
.light-label { color: #77deee; }
.format-title-block h2, .testing-section h2, .development-note h2 { color: white; }
.format-summary { max-width: 32rem; margin: 1.8rem 0 0; color: #aebbd5; font-size: 1.05rem; }
.format-list { border-top: 1px solid var(--line-dark); }
.format-list article {
  min-height: 10rem;
  padding: 2rem 0;
  border-bottom: 1px solid var(--line-dark);
  display: grid;
  grid-template-columns: 8.5rem 1fr auto;
  gap: 2rem;
  align-items: start;
}
.format-code {
  margin: 0;
  color: var(--cyan);
  font-size: 1.45rem;
  font-weight: 700;
  letter-spacing: -0.03em;
}
.gradient-code {
  color: transparent;
  background: linear-gradient(90deg, var(--cyan), #9e70ff);
  background-clip: text;
  -webkit-background-clip: text;
}
.format-list h3 { margin-bottom: 0.55rem; color: white; font-size: 1.4rem; line-height: 1.3; }
.format-list article div p { max-width: 30rem; margin-bottom: 0; color: #aebbd5; }
.physical-formats { padding-top: 2.2rem; }
.physical-formats > p { margin-bottom: 1rem; color: #77deee; font-size: 0.7rem; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; }
.physical-formats > div { display: grid; grid-template-columns: repeat(2, minmax(0, 1fr)); gap: 0.7rem; }
.physical-formats span {
  min-height: 4.8rem;
  padding: 0.85rem 1rem;
  border: 1px solid var(--line-dark);
  background: rgba(8, 24, 63, 0.62);
  display: flex;
  flex-direction: column;
  justify-content: center;
}
.physical-formats span:last-child { grid-column: 1 / -1; }
.physical-formats strong { color: white; font-size: 0.94rem; line-height: 1.35; }
.physical-formats small { margin-top: 0.2rem; color: #8f9fbd; font-size: 0.72rem; line-height: 1.4; }
.status-pill, .coming-soon {
  display: inline-flex;
  align-items: center;
  min-height: 1.8rem;
  padding: 0.3rem 0.65rem;
  border: 1px solid rgba(132, 218, 239, 0.38);
  border-radius: 99rem;
  color: #9fe9f3;
  font-size: 0.68rem;
  font-weight: 700;
  letter-spacing: 0.08em;
  line-height: 1;
  text-transform: uppercase;
  white-space: nowrap;
}

.product-section { background: var(--pale); }
.product-header {
  margin-bottom: clamp(3.5rem, 7vw, 6.5rem);
  display: grid;
  grid-template-columns: minmax(24rem, 1.2fr) minmax(18rem, 0.52fr);
  gap: clamp(3rem, 8vw, 9rem);
  align-items: end;
}
.product-header > p { margin: 0 0 0.4rem; color: var(--muted); }
.product-grid { display: grid; gap: 2.2rem; }
.product {
  min-height: 34rem;
  border: 1px solid var(--line);
  background: white;
  display: grid;
  grid-template-columns: minmax(20rem, 0.78fr) minmax(26rem, 1.22fr);
  overflow: hidden;
}
.product-liver { grid-template-columns: minmax(26rem, 1.22fr) minmax(20rem, 0.78fr); }
.product-copy {
  padding: clamp(2.4rem, 5vw, 5rem);
  display: flex;
  flex-direction: column;
  justify-content: center;
}
.product-topline { margin-bottom: 3.3rem; display: flex; justify-content: space-between; align-items: center; gap: 1rem; }
.product-topline > span:first-child { color: var(--muted); font-size: 0.72rem; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; }
.coming-soon { border-color: #bdafe9; color: #6246bd; background: #f5f1ff; }
.product h3 { margin-bottom: 1rem; font-size: clamp(2rem, 3.2vw, 3.5rem); letter-spacing: -0.045em; line-height: 1; }
.product-copy > p { color: var(--muted); }
.product ul { margin: 1.2rem 0 0; padding: 1.3rem 0 0; border-top: 1px solid var(--line); list-style: none; }
.product li { position: relative; padding: 0.4rem 0 0.4rem 1.4rem; color: #31415f; font-size: 0.93rem; font-weight: 700; }
.product li::before { content: ""; position: absolute; left: 0; top: 1rem; width: 0.55rem; height: 2px; background: linear-gradient(90deg, var(--blue), var(--violet)); }
.product figure { margin: 0; min-height: 32rem; background: #f5f5f6; }
.product figure img { width: 100%; height: 100%; object-fit: cover; }
.product-disclaimer { max-width: 63rem; margin: 1.4rem 0 0; color: #78849a; font-size: 0.82rem; }

.organ-section { background: white; }
.organ-heading {
  margin-bottom: clamp(3.5rem, 7vw, 6.5rem);
  display: grid;
  grid-template-columns: minmax(24rem, 1.2fr) minmax(18rem, 0.52fr);
  gap: clamp(3rem, 8vw, 9rem);
  align-items: end;
}
.organ-heading > p { margin: 0 0 0.4rem; color: var(--muted); }
.organ-grid {
  display: grid;
  grid-template-columns: repeat(5, minmax(0, 1fr));
  border-top: 1px solid var(--line);
  border-left: 1px solid var(--line);
}
.organ-card {
  position: relative;
  min-height: 31rem;
  padding: 1.25rem;
  border-right: 1px solid var(--line);
  border-bottom: 1px solid var(--line);
  background: #fbfcff;
  display: flex;
  flex-direction: column;
}
.organ-card-featured { background: linear-gradient(180deg, #f4fbff, #fbfcff 72%); }
.organ-card-featured::before {
  content: "";
  position: absolute;
  top: -1px;
  left: -1px;
  right: -1px;
  height: 3px;
  background: linear-gradient(90deg, var(--cyan), var(--blue), var(--violet));
}
.organ-art {
  height: 13.5rem;
  margin-bottom: 1.6rem;
  display: grid;
  place-items: center;
  overflow: hidden;
  background: radial-gradient(circle, rgba(24, 199, 232, 0.11), rgba(36, 91, 255, 0.03) 55%, transparent 72%);
}
.organ-art img { width: 100%; height: 100%; object-fit: contain; }
.organ-number { margin-bottom: 0.55rem; color: var(--blue); font-size: 0.7rem; font-weight: 700; letter-spacing: 0.12em; }
.organ-card h3 { margin-bottom: 0.7rem; font-size: 2rem; letter-spacing: -0.04em; line-height: 1; }
.organ-card > p:not(.organ-number) { margin-bottom: 1.4rem; color: var(--muted); font-size: 0.92rem; line-height: 1.55; }
.organ-card > span {
  margin-top: auto;
  padding-top: 1rem;
  border-top: 1px solid var(--line);
  color: #6246bd;
  font-size: 0.69rem;
  font-weight: 700;
  letter-spacing: 0.08em;
  line-height: 1.45;
  text-transform: uppercase;
}
.portfolio-note { margin: 1.25rem 0 0; color: #78849a; font-size: 0.82rem; }

.testing-section { background: var(--navy); color: #aebbd3; }
.testing-intro {
  display: grid;
  grid-template-columns: 0.22fr minmax(22rem, 0.9fr) minmax(20rem, 0.7fr);
  gap: clamp(2rem, 5vw, 6rem);
  background:
    linear-gradient(rgba(7, 19, 52, 0.93), rgba(7, 19, 52, 0.95)),
    url("./fibroblast-macrophage-background.webp") center / cover no-repeat;
}
.section-marker-dark { color: rgba(112, 149, 220, 0.18); }
.testing-intro .lead { color: white; }
.testing-intro > div:last-child { padding-top: 2.4rem; }
.testing-intro > div:last-child p:last-child { margin-bottom: 0; }
.challenge-path {
  padding-top: 0;
  padding-bottom: clamp(5rem, 8vw, 8rem);
  display: grid;
  grid-template-columns: repeat(3, 1fr);
}
.challenge-path article {
  position: relative;
  min-height: 15rem;
  padding: 2.2rem clamp(1.5rem, 3vw, 3rem);
  border-top: 1px solid var(--line-dark);
  border-right: 1px solid var(--line-dark);
  border-bottom: 1px solid var(--line-dark);
  background: rgba(12, 29, 73, 0.52);
}
.challenge-path article:first-child { border-left: 1px solid var(--line-dark); }
.challenge-path article:nth-child(2) { background: linear-gradient(145deg, rgba(36, 91, 255, 0.2), rgba(123, 72, 243, 0.13)); }
.challenge-path article p { margin-bottom: 2.8rem; color: var(--cyan); font-size: 0.7rem; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; }
.challenge-path h3 { margin-bottom: 0.7rem; color: white; font-size: clamp(1.4rem, 2vw, 2rem); letter-spacing: -0.035em; line-height: 1.15; }
.challenge-path span { display: block; color: #9eadc8; font-size: 0.92rem; line-height: 1.55; }
.testing-solution {
  padding-top: 0;
  display: grid;
  grid-template-columns: minmax(24rem, 1.15fr) minmax(20rem, 0.7fr);
  gap: clamp(3rem, 8vw, 9rem);
  align-items: end;
}
.testing-solution .lead { margin-bottom: 0.45rem; color: white; }
.testing-workflow { padding-top: clamp(1rem, 2vw, 2rem); }
.fibrosis-organ-figure {
  margin: 0;
  overflow: hidden;
  border: 1px solid var(--line-dark);
  background: #04102d;
  box-shadow: 0 2rem 7rem rgba(0, 0, 0, 0.24);
}
.fibrosis-organ-figure img { width: 100%; height: auto; }
.fibrosis-organ-figure figcaption { margin: 0; padding: 1rem 1.2rem; border-top: 1px solid var(--line-dark); color: #91a0bc; font-size: 0.82rem; line-height: 1.5; }
.study-strip {
  margin-top: 3.8rem;
  border-top: 1px solid var(--line-dark);
  border-bottom: 1px solid var(--line-dark);
  display: grid;
  grid-template-columns: repeat(4, 1fr);
}
.study-strip p {
  margin: 0;
  min-height: 8rem;
  padding: 1.6rem;
  border-right: 1px solid var(--line-dark);
  display: flex;
  flex-direction: column;
  justify-content: center;
  color: #d8e2f2;
  font-size: 0.94rem;
  font-weight: 700;
  line-height: 1.45;
}
.study-strip p:last-child { border-right: 0; }
.study-strip span { margin-bottom: 0.4rem; color: var(--cyan); font-size: 0.68rem; letter-spacing: 0.12em; }
.testing-audience { max-width: 60rem; margin: 2.4rem auto 0; color: #aebbd3; font-size: 1.05rem; text-align: center; }

.team-section {
  display: grid;
  grid-template-columns: 0.22fr minmax(20rem, 0.75fr) minmax(30rem, 1fr);
  gap: clamp(2rem, 5vw, 6rem);
}
.team-heading h2 { font-size: clamp(2.7rem, 4.2vw, 4.8rem); }
.founders { border-top: 1px solid var(--line); }
.founders article { padding: 2.1rem 0; border-bottom: 1px solid var(--line); }
.founder-role { margin-bottom: 0.8rem; color: var(--blue); font-size: 0.72rem; font-weight: 700; letter-spacing: 0.12em; text-transform: uppercase; }
.founders h3 { margin-bottom: 0.8rem; font-size: 1.75rem; letter-spacing: -0.03em; }
.founders article > p:last-child { max-width: 39rem; margin-bottom: 0; color: var(--muted); }

.development-note {
  min-height: 30rem;
  margin: 0 clamp(1.2rem, 2.5vw, 2.5rem);
  background:
    radial-gradient(circle at 92% 20%, rgba(24, 199, 232, 0.42), transparent 28rem),
    linear-gradient(115deg, #1438b9, #643de3 78%);
  color: white;
  display: grid;
  grid-template-columns: minmax(25rem, 1.25fr) minmax(18rem, 0.55fr);
  gap: clamp(3rem, 8vw, 9rem);
  align-items: end;
}
.development-note h2 { max-width: 57rem; }
.development-note > p { max-width: 32rem; margin-bottom: 0.6rem; color: #e2e8ff; font-size: 1.06rem; }

footer {
  padding: 3.5rem clamp(1.5rem, 5vw, 5rem);
  display: grid;
  grid-template-columns: minmax(14rem, 1fr) auto auto;
  gap: 3rem;
  align-items: center;
  color: var(--muted);
  font-size: 0.8rem;
}
footer p { margin: 0; }
.footer-brand { width: 15rem; }

@media (prefers-reduced-motion: reduce) {
  html { scroll-behavior: auto; }
  *, *::before, *::after { transition-duration: 0.01ms !important; animation-duration: 0.01ms !important; }
}

@media (max-width: 1120px) {
  .site-header { grid-template-columns: 1fr auto; }
  .header-status { display: none; }
  .hero-copy { padding-left: 3.5rem; padding-right: 3.5rem; }
  .hero-facts p:first-child { padding-left: 3.5rem; }
  .materials-intro, .testing-intro, .team-section { grid-template-columns: 0.18fr 0.9fr 0.8fr; }
  .format-inner { grid-template-columns: 0.72fr 1fr; }
  .format-list article { grid-template-columns: 7rem 1fr; }
  .format-list .status-pill { grid-column: 2; justify-self: start; }
  .organ-grid { grid-template-columns: repeat(3, minmax(0, 1fr)); }
}

@media (max-width: 900px) {
  .site-header { min-height: 5.8rem; padding-block: 0.85rem; }
  .brand { width: 14.5rem; }
  .hero {
    min-height: auto;
    padding-top: 5.8rem;
    grid-template-rows: minmax(37rem, 1fr) auto;
    background-position: 58% center;
  }
  .hero::before {
    background:
      linear-gradient(90deg, rgba(4, 11, 33, 0.97) 0%, rgba(5, 15, 43, 0.82) 67%, rgba(3, 9, 28, 0.55) 100%),
      linear-gradient(0deg, rgba(3, 10, 31, 0.7), transparent 45%);
  }
  .hero-copy { padding: 5.5rem 2.5rem 4rem; }
  .hero-facts p:first-child { padding-left: 2.5rem; }
  .materials-intro, .testing-intro, .team-section {
    grid-template-columns: 0.18fr 1fr;
  }
  .materials-explainer, .testing-intro > div:last-child, .founders { grid-column: 2; }
  .format-inner { grid-template-columns: 1fr; min-height: auto; }
  .product, .product-liver { grid-template-columns: 1fr; }
  .product-liver figure { grid-row: 2; }
  .product figure { min-height: 28rem; }
  .product-header { grid-template-columns: 1fr; gap: 2rem; }
  .organ-heading { grid-template-columns: 1fr; gap: 2rem; }
  .organ-grid { grid-template-columns: repeat(2, minmax(0, 1fr)); }
  .challenge-path { grid-template-columns: 1fr; }
  .challenge-path article { min-height: auto; border-left: 1px solid var(--line-dark); border-bottom: 0; }
  .challenge-path article:last-child { border-bottom: 1px solid var(--line-dark); }
  .testing-solution { grid-template-columns: 1fr; gap: 2.5rem; }
  .study-strip { grid-template-columns: repeat(2, 1fr); }
  .study-strip p:nth-child(2) { border-right: 0; }
  .study-strip p:nth-child(-n + 2) { border-bottom: 1px solid var(--line-dark); }
  .development-note { grid-template-columns: 1fr; align-items: start; }
  footer { grid-template-columns: 1fr; gap: 1rem; }
}

@media (max-width: 680px) {
  .site-header { grid-template-columns: 1fr auto; }
  .brand { width: 12.8rem; }
  .menu-button {
    display: grid;
    width: 2.65rem;
    height: 2.65rem;
    padding: 0;
    place-content: center;
    gap: 0.4rem;
    border: 1px solid var(--line);
    border-radius: 50%;
    background: white;
  }
  .menu-button span:not(.sr-only) { display: block; width: 1rem; height: 2px; background: var(--ink); transition: transform 160ms ease; }
  .menu-button[aria-expanded="true"] span:nth-child(2) { transform: translateY(0.2rem) rotate(45deg); }
  .menu-button[aria-expanded="true"] span:nth-child(3) { transform: translateY(-0.2rem) rotate(-45deg); }
  .site-nav {
    display: none;
    position: absolute;
    top: 5.8rem;
    left: 0;
    right: 0;
    min-height: calc(100svh - 5.8rem);
    padding: 2.5rem 1.5rem;
    background: rgba(255, 255, 255, 0.99);
    align-content: start;
    justify-content: stretch;
    gap: 0;
  }
  .site-nav.is-open { display: grid; }
  .site-nav a { padding: 1rem 0; border-bottom: 1px solid var(--line); font-size: 1.25rem; }
  .site-nav a::after { display: none; }
  .hero-copy { padding: 4.5rem 1.5rem 3.8rem; }
  h1 { font-size: clamp(2.85rem, 13.2vw, 4.9rem); }
  .hero { grid-template-rows: minmax(39rem, 1fr) auto; background-position: 61% center; }
  .hero-facts { grid-template-columns: 1fr; }
  .hero-facts p, .hero-facts p:first-child { min-height: auto; padding: 1.15rem 1.5rem; border-right: 0; border-bottom: 1px solid rgba(171, 206, 240, 0.2); }
  .hero-facts p:last-child { border-bottom: 0; }
  .section { padding: 5rem 1.5rem; }
  .materials-intro, .testing-intro, .team-section { display: block; }
  .section-marker { margin-bottom: 3rem; }
  .materials-explainer, .testing-intro > div:last-child { padding-top: 2.5rem; }
  .format-inner { padding: 5rem 1.5rem; }
  .format-list article { grid-template-columns: 1fr; gap: 1rem; }
  .format-list .status-pill { grid-column: 1; }
  .physical-formats > div { grid-template-columns: 1fr; }
  .physical-formats span:last-child { grid-column: auto; }
  .product-header { margin-bottom: 3.5rem; }
  .product { min-height: auto; }
  .product-copy { padding: 2rem 1.5rem 2.5rem; }
  .product-topline { margin-bottom: 2.5rem; }
  .product figure { min-height: 20rem; }
  .organ-grid { grid-template-columns: 1fr; }
  .organ-card { min-height: 29rem; }
  .organ-art { height: 14rem; }
  .fibrosis-organ-figure figcaption { line-height: 1.5; }
  .study-strip { grid-template-columns: 1fr; }
  .study-strip p { min-height: 6.5rem; border-right: 0; border-bottom: 1px solid var(--line-dark); }
  .study-strip p:nth-child(2) { border-right: 0; }
  .study-strip p:nth-child(-n + 2) { border-bottom: 1px solid var(--line-dark); }
  .study-strip p:last-child { border-bottom: 0; }
  .development-note { min-height: 32rem; margin: 0 1rem; }
  .footer-brand { width: 13rem; }
}

@media (max-width: 430px) {
  .hero-actions { align-items: flex-start; flex-direction: column; gap: 1.1rem; }
  .button { width: 100%; }
  .product-topline { align-items: flex-start; flex-direction: column; }
}